Update: October 10, 2021 10:51 PM STI
Washington [US], Oct 10 (ANI): Researchers at Bristol Medical School: Population Health Sciences (PHS) and School of Psychological Science broke rumors and found that allergic diseases do not cause mental health traits, including anxiety, depression, bipolar disorder and schizophrenia or vice versa.
The results of the study were published in the journal “Clinical and Experimental Allergy”.
Allergic diseases such as asthma, atopic dermatitis and hay fever do not cause the onset of mental health problems or vice versa, according to the results of a new study conducted by the University of Bristol.
While previous studies have reported an observational relationship between mental health and common allergic diseases, until now the causal relationships have not yet been identified.
First, the team of researchers sought to isolate the effects of these allergic diseases by applying a scientific technique called Mendelian Randomization, which allowed them to identify genetic variants linked to these allergic diseases, and then studied how these variants were causally linked to the presence of mental disorders. health conditions based on a sample of 12,000 to 344,901 individuals.
Although the researchers identified observational associations between allergic diseases and mental health traits, these were not replicated in the team’s causal analysis. Little evidence of a causal relationship between the onset of allergic disease and mental health was found, suggesting that the observational associations found were due to confounding factors or other forms of bias.
The authors conclude that intervening during the initial presentation of an allergic disease is unlikely to improve mental health outcomes. Likewise, preventing the onset of mental health traits is unlikely to reduce the risk of allergic disease. However, more research is needed to determine whether intervening in the progression of allergic disease after its onset has a causal impact on mental health.
Dr Ashley Budu-Aggrey, Senior Research Associate at Bristol Medical School: PHS and lead author of the study said: “Common mental health disorders such as anxiety and depression are among the most important Contributors to the global disease burden and its allergic diseases have been on the rise for some time. Unraveling the nature of the relationship between allergic disease and mental health helps answer an important health question and suggests that the onset of allergic disease does not cause the onset of mental health traits or vice versa.
“However, this does not rule out a potential causal effect on disease progression that has not yet been studied and could help uncover new treatment strategies for allergic diseases or mental health traits,” added Dr Budu-Aggrey.
Lead author Dr Hannah Sallis, Senior Research Associate at the School of Psychological Science, Bristol, added: “The research used a combination of approaches and data from several studies. This helps to build our confidence in Determining whether allergic disease causes mental health problems, or vice versa, is important to ensure that resources and treatment strategies are targeted appropriately. “
The study was funded by grants from the Medical Research Council (MRC), the European Research Council (ERC), the National Institute for Health Research Bristol Biomedical Research Center (NIHR Bristol BRC), the Norwegian Research Council, the British Skin Foundation and the Academy of Medical Sciences. Springboard Award, which is supported by the Wellcome Trust, the Department for Business, Energy and Industrial Strategy, Global Challenges Research Fund and the British Heart Foundation. (ANI)